Bioss Inc.'s ENT2/SLC29A2 Polyclonal Antibody, HRP Conjugated is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry, Immunohistochemistry - fixed, and Immunohistochemistry - frozen. The ENT2/SLC29A2 Polyclonal Antibody, HRP Conjugated was generated using SLC29A2 as the antigen and it reacts with Mouse, and Rat.
Description
Equilibrative nucleoside transporters (ENTs) regulate many physiological processes and are widely distributed in mammals, plants, yeasts, insects, nematodes and protozoans. They enable facilitated diffusion of hydrophilic nucleosides, such as adenosine and nucleoside analogs, across cell membranes. ENTs are required for uptake of antiviral and anticancer nucleoside drugs and influence a variety of physiological processes, such as neurotransmission and platelet aggregation, by regulating the amount of adenoside available to cell surface receptors. Equilibrative nucleoside transporter 2 (ENT2), also designated solute carrier family 29 (nucleoside transporters), member 2, belongs to the SLC29A transporter family and is a mammalian ENT isoform. ENT2 mediates the equilibrative transport of hypoxanthine in addition to nucleosides and is purine-selective